Genetic and environmental contributions to dimensions of personality disorder
by
Livesley WJ, Jang KL, Jackson DN, Vernon PA.
Department of Psychiatry, Faculty of Medicine,
University of British Columbia, Vancouver, Canada.
Am J Psychiatry. 1993 Dec;150(12):1826-31.

ABSTRACT

OBJECTIVE: The authors estimated the heritability of the basic dimensions of personality disorder and the relative proportions of the variance attributable to genetic and environmental sources. METHOD: The subjects were 175 volunteer twin pairs (90 monozygotic and 85 dizygotic) from the general population. Each twin completed the Dimensional Assessment of Personality Pathology, a questionnaire that assesses 18 dimensions of personality disorder. The questionnaire was developed on the basis of factor analytic studies that identified a stable structure underlying personality disorders in clinical and nonclinical subjects. Structural equation model-fitting methods were used to estimate the influence of additive genetic, common environmental, and unique environmental effects. RESULTS: The estimates of broad heritability ranged from 0%, for conduct problems, to 64%, for narcissism. Behaviors associated with submissiveness and attachment problems had low heritability. For most dimensions, the best-fitting model was one that specified additive genetic and unique environmental effects. CONCLUSIONS: These results are similar to those reported for normal personality and suggest a continuity between normal and disordered personality.

BPD
Eugenics talk
Reprogenetics
Private eugenics
'Saviour siblings'
Personal genomics
Alzheimers Disease
Psychiatric genetics
Human self-domestication
Selecting potential children
Brain size/human evolution
Alzheimer's disease: resources
Transhumanism/Brave New World?
Francis Galton and contemporary eugenics
Gene therapy and performance enhancement
Preimplantation genetics and stem cell therapy
Genetic correlates of phenotypes in major depressive disorder

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